微生物?菌群研究和产业化的因果命门在哪里?请细看这5900字( 六 )


6.Wu,H., Esteve, E., Tremaroli, V., Khan, M.T., Caesar, R., Manneras-Holm, L., Stahlman,M., Olsson, L.M., Serino, M., Planas-Felix, M., et al. (2017). Metformin altersthe gut microbiome of individuals with treatment-naive type 2 diabetes,contributing to the therapeutic effects of the drug. Nat. Med. 23, 850.
7.Natividad,J.M., Agus, A., Planchais, J., Lamas, B., Jarry, A.C., Martin, R., Michel,M.L., Chong-Nguyen, C., Roussel, R., Straube, M., et al. (2018). Impaired ArylHydrocarbon Receptor Ligand Production by the Gut Microbiota Is a Key Factor inMetabolic Syndrome. Cell Metab. 28, 737–749.
8.Roager,H.M., Vogt, J.K., Kristensen, M., Hansen, L.B.S., Ibrugger, S., Maerkedahl,R.B., Bahl, M.L., Lind, M.V., Nielsen, R.L., Frokiaer, H., et al. (2019). Wholegrain-rich diet reduces body weight and systemic low-grade inflammation withoutinducing major changes of the gut microbiome: a randomized cross-over trial.Gut 68, 83–93.
9.Zhao,L.P., Zhang, F., Ding, X.Y., Wu, G.J., Lam, Y.Y., Wang, X.J., Fu, H.Q., Xue,X.H., Lu, C.H., Ma, J.L., et al. (2018). Gut bacteria selectively promoted bydietary fibers alleviate type 2 diabetes. Science 359, 1151–1156.
10.Uchimura,Y., Fuhrer, T., Li, H., Lawson, M.A., Zimmermann, M., Yilmaz, B., Zindel, J.,Ronchi, F., Sorribas, M., Hapfelmeier, S., et al. (2018). Antibodies SetBoundaries Limiting Microbial Metabolite Penetration and the Resultant MammalianHost Response. Immunity 49, 545–559.
11.Khan,M.T., Nieuwdorp, M., and Backhed, F. (2014). Microbial Modulation of Insulin Sensitivity.Cell Metab. 20, 753–760.
12.Backhed,F., Manchester, J.K., Semenkovich, C.F., and Gordon, J.I. (2007). Mechanismsunderlying the resistance to diet-induced obesity in germ-free mice. Proc.Natl. Acad. Sci. USA 104, 979–984.
13.Turnbaugh,P.J., Ley, R.E., Mahowald, M.A., Magrini, V., Mardis, E.R., and Gordon, J.I.(2006). An obesity-associated gut microbiome with increased capacity for energyharvest. Nature 444, 1027–1031.
14.Ridaura,V.K., Faith, J.J., Rey, F.E., Cheng, J.Y., Duncan, A.E., Kau, A.L., Griffin,N.W., Lombard, V., Henrissat, B., Bain, J.R., et al. (2013). Gut Microbiotafrom Twins Discordant for Obesity Modulate Metabolism in Mice. Science 341, https://doi.org/10.1126/science.1241214.
15.vanNood, E., Vrieze, A., Nieuwdorp, M., Fuentes, S., Zoetendal, E.G., de Vos, W.M.,Visser, C.E., Kuijper, E.J., Bartelsman, J.F.W.M., Tijssen, J.G.P., et al. (2013).Duodenal Infusion of Donor Feces for Recurrent Clostridium difficile. N. Engl.J. Med. 368, 407–415.
16.Alang,N., and Kelly, C.R. (2015). Weight Gain After Fecal Microbiota Transplantation.Open Forum Infect Di 2 2, https://doi.org/10.1093/ofid/ofv004.
17.Vrieze,A., Van Nood, E., Holleman, F., Salojarvi, J., Kootte, R.S., Bartelsman, J.F.W.M.,Dallinga-Thie, G.M., Ackermans, M.T., Serlie, M.J., Oozeer, R., et al. (2012).Transfer of Intestinal Microbiota From Lean Donors Increases Insulin Sensitivityin Individuals With Metabolic Syndrome. Gastroenterology 143, 913–916.
18.DeFilipp,Z., Bloom, P.P., Torres Soto, M., Mansour, M.K., Sater, M.R.A., Huntley, M.H.,Turbett, S., Chung, R.T., Chen, Y.-B., and Hohmann, E.L. (2019). Drug-ResistantE. coli Bacteremia Transmitted by Fecal Microbiota Transplant. N. Engl. J. Med.381, 2043–2050.