Lancet子刊:长期进行结直肠癌筛查,相关死亡率降幅明显丨肿瘤情报( 三 )


2018年9月25日至2019年7月26日期间 , 共筛选出543例患者 , 其中357例患者被随机分配至信迪利单抗-GP组(n=179)和安慰剂-GP组(n=178) 。
中位随访12.9个月后 , 与安慰剂-GP组相比 , 信迪利单抗-GP组持续显示有PFS改善 , 差异有统计学意义(HR:0.536;95%CI 0.422-0.681;p
参考文献:
[1]https://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(21)00199-6/fulltext
[2] https://www.jto.org/article/S1556-0864(21)02174-2/fulltext
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[4] Caicun Zhou, Lin Wu, Yun Fan, Zhehai Wang, Lianke Liu, Gongyan Chen, Li Zhang, Dingzhi Huang, Shundong Cang, Zhixiong Yang, Jianying Zhou, Chengzhi Zhou, Baolan Li, Juan Li, Min Fan, Jiuwei Cui, Yuping Li, Hui Zhao, Jian Fang, Jianxin Xue, Chengping Hu, Ping Sun, Yingying Du, Hui Zhou, Shuyan Wang, Wen Zhang,Sintilimab plus platinum and gemcitabine as first-line treatment for advanced or metastatic squamous non-small-cell lung cancer: results from a randomized, double-blind, phase 3 trial (ORIENT-12),Journal of Thoracic Oncology,2021.
本文首发:医学界肿瘤频道
本文作者:肿瘤情报组
本文审核:徐蔚然 北京大学国际医院肿瘤内科
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